Two 21-year-olds, Edmund Ludick and Luyolo Dapula, are set to make their Pro14 debuts for the Kings against Munster in Cork on Friday.
Ludick replaces the injured Yaw Penxe on the left wing, with Dapula providing loose-forward cover from the bench.
Erich Cronjé shifts from wing to inside centre, while Christopher Hollis comes in on the right wing.
Lusanda Badiyana and Bobby de Wee will start in the loose trio alongside Ruaan Lerm, who is set to earn his 50th Kings cap.
Kick-off is at 21:35 (SA time).
Kings – 15 Andell Loubser, 14 Chris Hollis, 13 Sibusiso Sithole, 12 Erich Cronjé, 11 Eddie Ludick, 10 Demetri Catrakilis, 9 Stefan Ungerer, 8 Ruaan Lerm, 7 Bobby de Wee, 6 Lusanda Badiyana, 5 JC Astle (c), 4 Jerry Sexton, 3 Rossouw de Klerk, 2 Jacques du Toit, 1 Schalk Ferreira.
Subs: 16 Alandre van Rooyen, 17 Xandre Vos, 18 Ignatius Prinsloo, 19 Aston Fortuin, 20 Thembelani Bholi, 21 Luyolo Dapula, 22 Josh Allderman, 23 Courtney Winnaar.